| 2023-10 |
Failure, Success, and Future Direction of Alzheimer Drugs Targeting Amyloid‐β Cascade: Pros and Cons of Chemical and Biological Modalities |
ChemBioChem
|
| 2023-08 |
Benzo[d]imidazole-pyrrolo[1,2-a]pyrazine Hybrids Ameliorate Amyloid Aggregates in the Brain of Alzheimer Transgenic Mice |
ACS Chemical Neuroscience
|
| 2023-08 |
Inhibition of CXXC5 function rescues Alzheimer's disease phenotypes by restoring Wnt/β-catenin signaling pathway |
Pharmacological Research
|
| 2023-07 |
Carprofen alleviates Alzheimer-like phenotypes of 5XFAD transgenic mice by targeting the pathological hallmarks induced by amyloid-β aggregation |
Scientific Reports
|
| 2023-05 |
4-Acyl-3,4-dihydropyrrolo[1,2-a]pyrazine Derivative Rescued the Hippocampal-Dependent Cognitive Decline of 5XFAD Transgenic Mice by Dissociating Soluble and Insoluble A beta Aggregates |
ACS Chemical Neuroscience
|
| 2023-04 |
Nanotechnology and machine learning enable circulating tumor cells as a reliable biomarker for radiotherapy responses of gastrointestinal cancer patients |
Biosensors and Bioelectronics
|
| 2023-02 |
Glycosylated and Succinylated Macrocyclic Lactones with Amyloid-β-Aggregation-Regulating Activity from a Marine Bacillus sp. |
Marine Drugs
|
| 2023-02 |
Amyloid Against Amyloid: Dimeric Amyloid Fragment Ameliorates Cognitive Impairments by Direct Clearance of Oligomers and Plaques |
Angewandte Chemie - International Edition
|
| 2023-01 |
Immobilized Amyloid Hexamer Fragments to Map Active Sites of Amyloid-Targeting Chemicals |
ACS Chemical Neuroscience
|
| 2023-01 |
A Therapeutic Nanovaccine that Generates Anti‐Amyloid Antibodies and Amyloid‐specific Regulatory T Cells for Alzheimer's Disease |
Advanced Materials
|
| 2023-01 |
Solid-phase synthesis and pathological evaluation of pyroglutamate amyloid-β3-42 peptide |
Scientific Reports
|
| 2022-11 |
Aryloxypropanolamine targets amyloid aggregates and reverses Alzheimer-like phenotypes in Alzheimer mouse models |
Alzheimer's Research and Therapy
|
| 2022-05 |
Branched, dendritic, and hyperbranched polymers in liquid biopsy device design |
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
|
| 2022-04 |
Physiological Roles of Monomeric Amyloid-β and Implications for Alzheimer’s Disease Therapeutics |
Experimental Neurobiology
|
| 2022-04 |
Chemical-Driven Outflow of Dissociated Amyloid Burden from Brain to Blood |
ADVANCED SCIENCE
|
| 2022-03 |
Dendrimers for cancer immunotherapy: Avidity-based drug delivery vehicles for effective anti-tumor immune response |
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
|
| 2021-11 |
Anti-amyloidogenic indolizino[3,2-: C] quinolines as imaging probes differentiating dense-core, diffuse, and coronal plaques of amyloid-β |
RSC Medicinal Chemistry
|
| 2021-11 |
Bias-generating factors in biofluid amyloid-β measurements for Alzheimer’s disease diagnosis |
Biomedical Engineering Letters
|
| 2021-08 |
Azetidine-Bearing Non-Ribosomal Peptides, Bonnevillamides D and E, Isolated from a Carrion Beetle-Associated Actinomycete |
JOURNAL OF ORGANIC CHEMISTRY
|
| 2021-07 |
Validation of Fucoxanthin from Microalgae Phaeodactylum tricornutum for the Detection of Amyloid Burden in Transgenic Mouse Models of Alzheimer's Disease |
APPLIED SCIENCES-BASEL
|
| 2021-06 |
Quinacrine directly dissociates amyloid plaques in the brain of 5XFAD transgenic mouse model of Alzheimer's disease |
SCIENTIFIC REPORTS
|
| 2021-01 |
Thioflavin-positive tau aggregates complicating quantification of amyloid plaques in the brain of 5XFAD transgenic mouse model |
SCIENTIFIC REPORTS
|
| 2021-01 |
Borrelidin from Saltern-Derived Halophilic Nocardiopsis sp. Dissociates Amyloid-β and Tau Fibrils |
Journal of Alzheimer’s Disease Reports
|
| 2021-01 |
Orally Administered Benzofuran Derivative Disaggregated Aβ Plaques and Oligomers in the Brain of 5XFAD Alzheimer Transgenic Mouse |
ACS CHEMICAL NEUROSCIENCE
|
| 2020-12 |
Fluorescent indolizine derivative YI-13 detects amyloid-beta monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model |
PLOS ONE
|
| 2020-12 |
Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H2O2- production |
NATURE NEUROSCIENCE
|
| 2020-12 |
Rhizolutin, a Novel 7/10/6-Tricyclic Dilactone, Dissociates Misfolded Protein Aggregates and Reduces Apoptosis/Inflammation Associated with Alzheimer's Disease |
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
|
| 2020-12 |
Hair growth promotion by necrostatin-1s |
SCIENTIFIC REPORTS
|
| 2020-12 |
Investigation of memory-enhancing botanical mixture and their isolated compounds for inhibition of amyloid-β and tau aggregation |
Applied Biological Chemistry
|
| 2020-10 |
Bicine promotes rapid formation of beta-sheet-rich amyloid-beta fibrils |
PLOS ONE
|
| 2020-08 |
Elevated plasma biomarkers of inflammation in acute ischemic stroke patients with underlying dementia |
BMC NEUROLOGY
|
| 2020-07 |
Longitudinal profiling of oligomeric A beta in human nasal discharge reflecting cognitive decline in probable Alzheimer's disease |
SCIENTIFIC REPORTS
|
| 2020-07 |
Discovery of Chemicals to Either Clear or Indicate Amyloid Aggregates by Targeting Memory-Impairing Anti-Parallel Aβ Dimers |
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
|
| 2020-06 |
PyrPeg, a Blood-Brain-Barrier-Penetrating Two-Photon Imaging Probe, Selectively Detects Neuritic Plaques, Not Tau Aggregates |
ACS CHEMICAL NEUROSCIENCE
|
| 2020-04 |
Gold nanoparticles assisted sensitivity improvement of interdigitated microelectrodes biosensor for amyloid-beta detection in plasma sample |
SENSORS AND ACTUATORS B-CHEMICAL
|
| 2020-03 |
Alzheimer's Disease Diagnosis Using Misfolding Proteins in Blood |
Dementia and Neurocognitive Disorders(대한치매학회지)
|
| 2020-03 |
Destruction of ERP responses to deviance in an auditory oddball paradigm in amyloid infusion mice with memory deficits |
PLOS ONE
|
| 2020-01 |
Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson's Disease |
CURRENT BIOLOGY
|
| 2020-01 |
Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease. |
PLOS ONE
|
| 2019-08 |
Preventive approach for overcoming dementia |
ARCHIVES OF PHARMACAL RESEARCH
|
| 2019-06 |
Fluorescence Chemicals to Detect Insoluble and Soluble Amyloid-β Aggregates |
ACS CHEMICAL NEUROSCIENCE
|
| 2019-06 |
Fluorescent 1,4-naphthoquinones to visualize diffuse and dense-core amyloid plaques in APP/PS1 transgenic mouse brains |
ACS CHEMICAL NEUROSCIENCE
|
| 2019-05 |
Diagnosis of Alzheimer’s disease utilizing amyloid and tau as fluid biomarkers |
EXPERIMENTAL AND MOLECULAR MEDICINE
|
| 2019-04 |
Comparative analyses of plasma amyloid-β levels in heterogeneous and monomerized states by interdigitated microelectrode sensor system |
SCIENCE ADVANCES
|
| 2019-03 |
A small molecule Nec-1 directly induces amyloid clearance in the brains of aged APP/PS1 mice |
SCIENTIFIC REPORTS
|
| 2019-03 |
Dielectrophoresis-based filtration effect and detection of amyloid beta in plasma for Alzheimer's disease diagnosis |
BIOSENSORS & BIOELECTRONICS
|
| 2019-02 |
Frontiers in Probing Alzheimer's Disease Biomarkers with Fluorescent Small Molecules |
ACS Central Science
|
| 2018-12 |
Peptide-nanoparticle conjugates: a next generation of diagnostic and therapeutic platforms? |
Nano Convergence
|
| 2018-08 |
TNF-alpha increases the intrinsic excitability of cerebellar Purkinje cells through elevating glutamate release in Bergmann Glia |
SCIENTIFIC REPORTS
|
| 2018-06 |
Multifunctionalized Reduced Graphene Oxide Biosensors for Simultaneous Monitoring of Structural Changes in Amyloid-β 40 |
SENSORS
|
| 2018-01 |
Identification of Plasma Membrane Glycoproteins Specific to Human Glioblastoma Multiforme Cells Using Lectin Arrays and LC-MS/MS |
PROTEOMICS
|
| 2018-01 |
Four-week individual caging of male ICR mice alters body composition without change in body mass |
SCIENTIFIC REPORTS
|
| 2017-09 |
Preliminary PET Study of F-18-FC119S in Normal and Alzheimer's Disease Models |
MOLECULAR PHARMACEUTICS
|
| 2017-08 |
Taurine directly binds to oligomeric amyloid-β and recovers cognitive deficits in Alzheimer model mice |
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY
|
| 2017-08 |
Taurine-carbohydrate derivative stimulates fibrillogenesis of amyloid-β and reduce Alzheimer-like behaviors |
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY
|
| 2017-08 |
A highly sensitive plasma-based amyloid-beta detection system through medium-changing and noise cancellation system for early diagnosis of the Alzheimer's disease |
SCIENTIFIC REPORTS
|
| 2017-06 |
Enhancing surface functionality of reduced graphene oxide biosensors by oxygen plasma treatment for Alzheimer's disease diagnosis |
BIOSENSORS & BIOELECTRONICS
|